Does Blender take advange of CPU instruction sets?

Does Blender 2.7x take advange of any / all of the following instruction sets and if so which ones?
MMX
SSE
SSE2
SSE3
SSE4.1
SSE4.2
AVX
FMA3
FMA4
EM64T
F16C
AVX2.0
AES

and should i worry about this when deciding on a CPU?

Modern CPU’s should pretty much support all of those.

Exceptions might be AVX and AVX2, but the only part of Blender that uses them is Cycles and has fallbacks to SSE instructions if it’s not supported on your machine.

Yes it does. SSE2 is also a minimum requirement. Don’t know more specifically than that.