I’m Sorry for not been more extensive on the explanation. But the edit-mode tools are just so many and with so many uses that I would need to, at least, see a wireframe of your model so I can give more specific advice.
Just to give you an overview off those tools are:
Basic ‘Pure’ Tools:
Extrude (E)
Scale (S)
Grab (G)
Rotate ®
Shear (Ctrl-S)
Wrap/Bend (Shif-W)
Blow
Smooth
Shrink/Fatten (Alt-S)
Split (Y)
Separate §
Make Face/Edge (F)
Make Vertex
Triangulate (Ctrl-T)
Not ‘Pure’ Tools:
Fill and Sub-Divide… more on that later.
About the ‘pure’ tools, most of them don’t only have a normal lineal mode, but also a proportional (magnetic) mode, and there are 2 types of magnetic attraction.
To complicate things a little, almost all of them, besides the lineal/proportional thing, there are 4 global modifiers of the tool’s behavior, namely: ‘around boundbox center’, ‘around mediant point’, ‘around the cursor’ and ‘around individual center’… all 4 yielding very different results.
Note: Wrap and Blow allways operate ‘around the cursor’ while Shrink/Fatten is never influenced by those modifiers (I think so).
The ‘un-pure’ tools: Personally, I consider Fill and Subdive to be ‘unrefined’ tools because, 99% of the times that you use them you need to use other tools just to fix the result that they produce.
Fill (Shif-F) usually needs to be followed by a Beauty Fill (Alt-F), plus one or more Triangulate, Quadrangulate and Rotate Edges (that are dangerous by themself) just to get an nearly usefull mesh.
Sub-Divide, while been better behaved than Fill, also usually needs a lot of fixing & cleaning on the borders of sub-divided area.
Sub-Divide comes in plain, ‘Beauty’, ‘Fractal’ and ‘Smooth’ flavors, from those the ‘Beauty’ is my favorite because it does a great effort to only cut the faces along just one axis and produce nice quads, so you end with less mess to clean up later.
Feelling dizzy already? Wait untill you read the release notes of Blender 2.28… there are many new hotkeys and variations to the tools already present… God, we need an updated documentation ASAP!!!