I started playing with an attempt to make an entire human, including bones and organs and muscles, from the skin modifier. No reason, I just need a project to keep my mind off life’s burdens right now.
Here you can see the skeleton so far. Usually these are going to be made from the following stack: Mirror, subdivision, Skin, subdivision.
For more complex shapes (like the shoulder blade) I might do a skin-specific boolean modeling fakeout, with the following stack: Mirror, subdivision, skin, subdivision, remesh, smooth.
Thinking about pipeline uses…sculpting all the skin mod vert chains for quick, but dynamically anatomical, base meshes.