I have experienced the Nvidia Forceware 190.38 WHQL XP Driver, Blender 2.49 opens, starts, shortly after movement of anything gets slow or locks up for periods of time. Did not try other 3d applications. Not sure if it has anything to do with the driver. I reverted to the Forceware 186.18 & everything works fine. Just a warning maybe it’s just my setup. It’s an older card, GeForce 6800.
Let me know if you have had the same problem.