Same problem… I updated CUDA drivers, and tried that Graphicall build (which crashed immediately). I even sent a message to the dev’s (hope I don’t annoy them)…
The Quadro 4000 supports the CUDA computing capability 2.0, which is supported by Blender in general.
But our official Mac builds don’t come with CUDA render kernels, so for now you have to rely on a build from graphicall.org, which contains the rendering kernels (just look for a build with the info “with CUDA” or something like that.