Blender can't open folder to save work

I have been able to save all my files up to now

but now when I try to save my work, blender is giving me a message in red at the bottom of the screen

that it cannot open the folder.

So I cannot save my work and I am unable to progress with my current project.

Any suggestions appreciated.

Suppose to save your work in a different place and then figure out what’s wrong with your folder?

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This happened just before my entire OS crashed.
I had to reinstall.
So I suspect an entire system failure had something to do with it.
I have not had to the problem after reinstalling my system.