Can I use images for the face instead of modeled eyes?

I’m going to be modeling an anime character named Hakase:

and I want to know how I should go about with the face. Should I use modeled eyes/mouths? Or can I model the head without a face, and use images for the face (eyes, mouth, and blush)? It’ll be changing in-game/animation to blink, talk, or change expressions.
Attack on Titan Tribute Game is using something like what I’m thinking of:

Sorry for so many questions and thank you! :o

For an anime-style character I’d say use textures for eyes. This is generally speaking, of course, as it can vary case-by-case. Based on what you’ve shown as references though, go with textures.