Now its not necessary anymore to make vertex group LEFT and RIGHT I need to combine
shapekeys for example (left side) shapekey smile.L combining with with shapekey smile.R (right side).
How can I do that.
Set the two shapes to 1 then use the ‘New Shape from Mix’ to create a new shape then delete the original shapes

Thanks your very helpful today.
Why did I not know that myself.
I think I need a short break.