Hello there,
I just finished to build Blender 2.60a from sources (in order to get Cycles), everything worked just fine except the software : once the build finished, I tried to launch Blender with “./bin/blender --factory-startup”, I got a white screen for less than one second and then the console said :
[[email protected] build]$ ./bin/blender --factory-startup
connect failed: No such file or directory
ndof: spacenavd not found
found bundled python: /home/martin/blender-cycles/build/bin/2.60/python
Fatal Python error: Py_Initialize: Unable to get the locale encoding
LookupError: no codec search functions registered: can't find encoding
Abandon (core dumped)
I’m not exactly a genius with computers and I don’t know what is the problem exactly, so if anyone could help… 
I’m on a laptop running Fedora 15 64-bits and I just followed the instructions there : http://wiki.blender.org/index.php/Dev:2.6/Source/Render/Cycles/Building