Crashing at Startup

Blender 2.45 is crashing at startup.
The DOS window starts and the blank Blender window appears but it crashes before the interface is shown.
It was working OK on my machine last week.
Athlon 3800, 2Gb, Nvidia 7600GS, XP SP2

The only thing I think I did was update the Nvidia driver to v169.21.
It has since been reverted to the previously working driver, v163.71.

I have removed Blender (including orphaned directories) twice and reinstalled twice.
I have re-installed vcred2005.

All my other CAD and graphics applications are working fine.

Any help would be appreciated.
Thanks Ray