Following your prompt I tried this out. I have tried using models with and without the SLI bridge between two 1080Ti’s.
Some more detailed info for anyone who stumbled across this topic when doing their research, I had some strange behavior when I installed my second card. Some of my Blender models had trouble loading after adding the second card, and was repeatedly receiving the same error:
"a graphics card and driver with support for opengl 3.3 or higher is required"
Despite having just updated my drivers the day before, after installing the card.
First I thought it was certainly an issue with SLI so I removed the bridge, but it continued.
I disabled one of the cards in device manager, then the models would load fine. But strangely it would work if I disabled either card, so my workaround was to disable one of the cards, load the model, save it, and then enable the card. Now it works with either or both cards, with or without SLI. This was reproducible the case for multiple models. I still have no idea why, very strange.
Hope this helps somebody dealing with a similar issue.