But i think that is not true.
If i go over the two buttons they say:
start time - simulation time of the first blender frame
end time - simulation time of the last blend frame
I think start time is something like “Simulation time passed when first frame starts”. E.g. so that there has been some flow out of the inflow when firstframe starts.
actually i believe that is so you can vary the physical time of simulation versus the keyframe time - ie do things like bullet time. Hmmm your inflow outflow idea is good too