first i was sceptic, but i love it since i tried - expression v3.3, now owned by microsoft.
the guys from redmont seem to haven’t touched a lot, as this proggie is really extremely efficient and easy to use. you can choose from various brushes and brush styles, rotate the view (!) and export vectors and bitmaps.
if you’re into artistic drawing and scribbles using your wacom, try it out.
the best thing - it’s still free (beta, but working perfectly), you’ll only need a .NET Passport registration (yea know this sucks but it’s worth it!)
it’s being rumored that this is the first step towards microsofts attempt for a FLASH-killer - we’ll see. right now it’s an Illustrator for free.