How do I use an x-rite card in Blender?

I wanted to adjust my colors and textures for my models but using this left me wondering how much light to use, what lights to use. I tried to use it to balance my textures then when I put my model in an actual scene it was shaded all wrong even after using the x-rite card. So I must have used it incorrectly.

So what is the practice of setting the lights and exposures?