How to make an image animation in blender

Hi,i was wondering how can I make an blinking eye animation for my character by using only a plane image.

I assume you mean sprite animation? This might be a good start…

one easy way, is using replace mesh, (not for some things) on the whole head, and have a half-blink and blinking head

this negates the plain, but won’t work to do a full range unless you have a lot of meshes,

(this does not use a plane)

I think switch mesh works on a plane as well?(change texture etc)