I have Blender 2.49 installed and Python 2.6.6 on Windows XP and Windows 7. Blender recognises my Python install (“Got it!”) on start up and I can import Numpy modules from the standard Python site-packages folder.
However, when I try to import GDAL modules, I get a dll load fail error. My GDAL libraries all work when I import them from PyWin32, Idle or at the Python command line.
I have tried GDAL libraries compiled using MSVC 2010 and 2005 (and Python 2.6 in both cases). I have set the PATH variable and they all work perfectly in a standard Python Interpreter, just not in Blender.