Is it possible to have multiple baked simulations existing together in different files?

Hello,
I baked a simulation using a cache file, and created a new file and a new cache to bake a second one. After the baking of my second one i’m coming back to my first file and constating that the first simulation is no longer baked. Is it a possibility to get two simulations baked at the same time, or creating a new bake (in a different file) will instantatly delete the other ? If it’s possible, should i keep the same cache for all my .blends containing bakes or get a different cache for each?

sorry if it’s simple but each simulation i do is very long (hours) so it’s a bit frustrating to don’t understand how it works. thanks!