Is it possible....

Is it possible to animate a 2D figurine? I’ve been using grease pencil and using different slides to make animations, but changing the appendages and other body parts after I’m done with a part is a real pain, and I need to know if there is another method; there’s also the problem of grease pencil not showing up in the Animation and Sequence; I’ve been discouraged about how my videos were made, and I want to improve them greatly.

Many ways to make your 3d animation look 2d in blender. If you want to draw a animation Id try pencil 4.4 program
http://www.pencil-animation.org/