Is Remesh and Symmetry Option disabled if you have Multires Modifier on your mesh?

Hi guys, i’m new to blender. may i ask if you have a multires modifier, will Remesh and Symmetry become greyed out. for me it got greyed out, so i can’t remesh if the polygons are already too far stretched.

also, in the symmetry i can’t click the symmetrize x to -x.

Use of multires modifier implies that no addition or suppression of mesh components is done on base mesh.
So, those remeshing operations are forbidden. That is intended behavior.