Mouse view...?

I’m not a newbie to blender, but I have a problem.
When I run the exe done by publisher, Then to apply the mouse is
Ctrl+F3, my problem is that I applied the mouse ‘once’ and now everytime
I open the exe the mouse is applied, I need to know how to un apply the
mouse. :frowning:

Run blender, un apply it as your first step, and save your user defaults by using Ctrl+U.

but how to unapply it (with what).