Check out my After Effects like setup on Blender:
I would like a genuine, after effects layout for blenders video stuff, a photoshop layout for image editing stuff, including object outliner to be like photoshop layer pannel… and a stienberg nuendo layout for the audio side of things.
one can dream.
Perhaps with 2.5…
unfortunatly I dont think so, a lot of the core functions are written not in python but in c++
but that said, you can do some customising in 2.5 with python… the post here shows how.