natural organic rigging

Hello, if I want to get a realistic organic movement of the face and body, is there any consideration while topologizing I should keep in mind? Or as long as I have good topology, I’m all set? Thanks

Apologies.i thought for each forum there is a one designated specialist for that subject, I thought for each forum, I have to ask for that specific subject. I didn’t know I could ask about multiple subjects In only one forum, but now i know.Thank you