Pixel art combined with UV mapping

Hello all!

I used this tutorial to learn how to render in pixel art: https://www.youtube.com/watch?v=Z3yOCJRaUxc

However, I never saw any way that I could do something like this in combination with a UV map. I would like to have a regular texture, although I can make my texture with mostly solid colors if it’s necessary to. Any help is appreciated.

Thank you!