I figured it out the most efficient way to make realistic fibers around fat cell recently.
Firstly I used shrinkwrap modifier to create shell mesh outside the cell mass, then I found expand cloth filter in sculpting mode is a much better solution than shrinkwrap
Cloth brush is really a game-changer! It makes it easier to create biological models.
And here is my other biomedical artworks ~
https://www.artstation.com/icrdr
Wow that looks very good. Can you explain a bit more how you use the cloth filter and brush to do this?
Sure! It is quite simple: first, add the “collision” property to the cell mass, then create a sphere that covers the cell mass, apply the expand cloth filter (reverse) in sculpting mode. It gives the effect like shrinkwrap but much more soomther.
Great image! What I am wondering is how you got the fiber texture itself, it looks really good. Is it procedural or an imagemap with a lot of transparency or what?
Incredible detail- very nice.
This reminds me of the time I accidentally slashed my finger open, and saw what looked a lot like that. I’d say it’s pretty realistic. Great job! 
I tried procedural way to generate fibers but failed. I need a more controlled way to distribute the fibers, so the texture paint with cobweb texture is much more faster and controllable in my view.
Many thanks!
That must be hurt! 
And thanks for the compliment!
I featured you on BlenderNation, have a great weekend!
