Reasons for Multires "Spiking" or "Exploding"

Can someone list all the causes when Multires sculpting produces unexpected popping of vertices? I’d like to use Multires+Armature in future animations, and want to be sure I won’t run in the situations where it generates artifacts. Last time I’ve seen it breaking, is when I added the modifier on the model posed with Armature, and sculpted it. I wonder if there can be more workflows that can result in that

You shouldn’t be using multires + armature anyway- once you’re done sculpting, retopologize into an animation-ready topology

The idea of being able to animate a sculpt is too appealing. Retopo + baking is a lot of work, plus inevitably leads to loss of quality

This is one of those “wouldn’t that be cool” ideas, that asks too much of the math and processor.

I didn’t ask if it is performant or not, only about conditions that cause Multires to break.