Remember that Blender is 3D program. The comic book frame you posted were hand rendered, and dark and light paten were created to serve the composition of the image. They are not real, 3D wise that is.
I did little test setup with Blender toon shader. Here is straight render. I did not try to smooth out the object. Hard edged faces do create more dramatic look with hard shadows. To get halftone gray pattern, you need to use Compositor; get an alpha map and fill with halftone. But then all that wrinkles on the clothing will need to be modeled!