Since Blender uses all of what it can out of a Wacom tablet, set it up as best you see fit.
To help you “see fit” check out these thoughts:
- You have a three-button mouse in the stylus - which do you want to be the middle button? You need to change that immediately;
- You can do pie menu with Wacom - this will take you some time and effort as others can’t offer much insight on how you work and what you want to access the quickest;
- Play, play, play - get used to using it by using it often. Only then can you figure out how soft you want it to be, how quickly to tap for a doubleclick, etc.
When you say a good way to navigate I would suggest knowing the shortcut keys that might assist in this.
Robert