Sculpting Shape Keys with Multires Modifier?

I’m modeling a character and doing expression tests with shape keys. She has a multires modifier and the sculpt mode changes I make to shape keys doesn’t seem to apply (or rather it messes up my base mesh). I looked up the topic and apparently multires is incompatible with shape keys, but this tutorial I’m following seems to do it just fine?

Can someone shed some light on this? I’m still a beginner. Is there a way to use shape keys without applying the multires and losing the low poly mesh? Would a subdivision modifier be compatible?