Setups of daily systems with different graphic cards

[YAFU (English is not my native language)]

If you are referring to for example OpenGL for Eevee, you investigate about render offload.
On Linux, having intel iGPU as primary display and using PRIME, I can launch Blender so that OpenGL is handled by nvidia card using render offload. I suppose that having two nvidia cards it should also be possible, that is, choosing which card will handle OpenGL when launching an application.
But this perhaps would be better to ask on nvidia forums, for example here for Linux:

Linux

I’m not sure where for Windows, maybe in this OpenGL section:

OpenGL

Edit:
If I remember correctly, someone had said that when you have two nvidia cards you could choose with which card to launch an application, and these OpenGL settings were made from the nvidia settings utility. You look for discussions about how to render with Eevee in multiple instances with different cards.

Edit 2:
Here it is for Windows:

Eevee and multiple graphics cards

On windows with GeForce drivers its really easy. Just open one Blender with GPU 1 and then switch the settings and open another Blender. Sometimes i use 8 Blenders simultaneously to get 100% gpu load with eevee rendering. [image] Most of the time is use a titan x for the viewport (monitor is connected), and render on my two 1080 TI, so i can surf the web without lag while rendering.