Simulate Particles within fluid flow

Hey guys,

Iam still quite new to Blender, learned to like it for modelling but now have a question concerning fluid/particle simulation - an area I never touched so far.
So, the scope is actually not to get beautifully looking results but to obtain information that are physically correct (we need these for scientific research) - I want to ask you if you can give a statement about if blender’s simulation features are suitable for our desires:

I want to simulate particles of defined sizes that flow in water through a filter - or rather a plate with defined holes. The distance between the holes is relatively large;e.g. we have holes of 50 µm diameter every 250 µm. We want to learn about the distribution of particles of different sizes when they are “filtered” through such a plate. Intuitively you would say that every particle smaller than the hole size would pass through and the rest stays on top, but due to the relatively large distance between the holes of course also smaller particles can simply stay in between the holes. What we need to do is optimize size of and distance between the holes, in accordance to the particles we need to filter in order to get best separation.
Fabricating the filter plates for real experiments is extremely expensive, unfortunately, so that we would like to get some rough information through adequate simulations.

Sooooo… here my questions in a (hopefully) precise form:

  1. Is it possible to have particles simulated within a fluid flow?
  2. Can the fluid / particle simulation be considered more or less physically correct?
  3. Is it possible to have the simulation being run at µm scale? If not… I guess, scaling everything up to mm space or so would be an approximation we could live with.

Thanks for your time and hopefully some replies in advance!
Best wishes, Hackmet!