“The uncanny valley hypothesis holds that when robots and other facsimiles of humans look and act almost like actual humans, it causes a response of revulsion among human observers. The “valley” in question is a dip in a proposed graph of the positivity of human reaction as a function of a robot’s lifelikeness.” - http://en.wikipedia.org/wiki/Uncanny_valley
People who look at this forum a lot can remember quite a few images that fall into the Uncanny Valley. I wont name names - the artists who create them are very skilled to even have got to the Uncanny Valley. Infact - one of the best uses of the uncanny valley is Gollum.
Realistic paintings and drawings can also inhabit the valley.