Using metric and imperial within the same blend file

I usually use imperial scaling when modeling. I usually do the following

-select imperial scaling
-create a 1’ x 1’ cube … apply scale to the cube
-create the rough outline of model to the appropriate size based on dimensions, and size the blueprint or reference
image to match.

But occasionally I will need to model a different object within the same blend file. Often the reference dimensions could be in metric.

So my question is if I set everything up using imperial, can I just flip back and forth between metric and imperial?

Of course you can, you can create a model with imperial, then switch to metric for another model, and then switch back to imperial.