Since I upgraded to version 2.82, I have run into a situation where I loose all ability to move my viewpoint in translation. Left-Right, Up-Down, Forward-Back all do not work. All I am able to do is rotate the viewpoint in place, (Pan, Tilt, and Roll). This prevents me from being able to place my viewpoint effectively for working on any model.
Did you reuse your old settings file from the prior versions? Then maybe reset to default settings wil help:
File -> Default -> Load factory settings.