2D mouth textures on 3d model?

Thinking of a short animation with 3d characters. I’ve seen the mouth tutorials like this one -

Is it feasible to put these textures on a 3d model? And if so How? If you can imagine the Lego movie they have 3d models with 2d mouth textures, that’s the kind of thing I’m after.

Cheers

Looks good reading! cheers bro!