2d textured faces

Hi I’m new to this forum and I was wondering if anyone could please help me with a problem that I’ve been trying to solve. I am trying to figure out a way to create the exact 2d facial expression as one of my favorite tv shows. The show being Jelly Jam. http://www.youtube.com/watch?v=8KMQvL1wWMU. I’ve looked throughout this forum and many others online without success. One of my friends who does 3d has already mentioned to me to maybe do it with texture blending but I just want to make sure that, that would be the best avenu to do it. If anyone could please point me to any tutorials or could give me any hints on how to do this in Blender I’d greatly appreciate it.