So, if I understand you correctly, you want to make an OS based around Blender? (I.e. Boot PC => Load OS => Only Blender)
If that is the case, it’s going to take quite some time and some patience. I think the best way to tackle it would be to create your own minimal/lightweight linux distro that loads in two stages: kernel(?), drivers (video, audio, net, hdd, I/O) first, and then a modified desktop environment that skips the taskbar-stuff and starts up Blender directly.
Evt. take a look at this: http://en.wikipedia.org/wiki/Lightweight_Linux_distribution - most of them should be able to be modified as they have an open source license.
- But as said, it would indeed require a lot of patience, as coding your own linux distro (let alone modifying existing) takes a lot of time and requires a nifty bunch of programming skills.
Also, why precisely are you interested in this (asking out of curiosity)? - Planning on making…sort of a mini-console? (Like a Raspberry Pi based thingy that loads a game? or just something quickly bootable from a USB device?)