In cycles I have and image texture applied to a model and it is also registering as a paint slot but when I try to paint on it nothing happens.
Have you added your new painted texture to your object’s material? You won’t see it in the Cycles render otherwise…
I did, I added it in the node editor.
It’s there but I can’t do anything to it.
Without more to go on, I’d need a blend file to look at. Or at least some screenshots…