Well I’m glad you explained the point of the picture. I wouldn’t have guessed it otherwise. The eyeball itself is expressionless, so I can’t get drawn to any type of feeling for it because it looks like it has no feeling. Its blank in expression…there’s no want to get to know the character.
As for dissecting the character, the way the chicken legs are attached to him, shows that he has no ability to look all around, which means his legs will become crossed if he looks around too far. The design is flawed in that aspect. However, saying that, the character is unique nonetheless. An eye on chicken legs. 
As for the lighting, it seems flat overall. The shadows are too sharp, even for studio lighting. The light bulb would have to be directly beside the eye in order to produce such sharp shadowing in real life. Even though it’s CG, you still need to consider real world elements to sell your shot. Although you said you wanted to stay away from dramatic lighting, you need to remember that lighting plays a significant role in CG and you don’t have to be all “dark and shadowy” to tell a story. Even compositing an AO pass over this image could have helped it drastically.
The character could have a better pose. I know he is leaning on that one leg, which is good because it helps sell the weight factor. But I do believe a slight “head tilt” (eye tilt in this case), would give more expression since he has no lids to convey emotion.
The studio could use more elements. Maybe bump on the walls, perhaps molding around the floor to separate the floor from the wall, just like in a real room. The mirror frame could use more work as well as its material. The way it looks now is almost showing depth and that it’s actually a cutout in the wall, making it almost appear as if its another room. If not for the reflection, it could be confusing.
The multicolored pictures on the wall are distracting, taking the viewer’s eye away from the…well, the eyeball guy. The framing could help sell the shot more, set tight on the eyeball and his easel along with the mirror. The rest is kind of a waste in the scene.
Good job and hope these crits help some on this or future projects.