If you have never tried the new Zbrush 3.1, you are in for a treat!!
Pixologic released a 30 day demo for you to download and try.
This software works best with a Tablet , but is still fun with just a mouse.
Check out the real time shadows!!! as you model, and sculpt, you get to see nice shadows with soft falloffs!
It also features a real time Cavity shader… AWESOME for seeing bumps and dents while sculpting!!
I would give almost anything for Realtime shadows and a cavity shader in blender!
Zbrush has a bit of an odd interface at first, just give it a little time and you will grow to love it!
anyways… have fun!