I actually know the person behind MOI - so if this application is what you want go for it. It also has very strong OBJ export features. Rhino offers a lot more in terms of tools but I feel MOI strikes a very good balance between needed tools and usability.
NURBS is a pretty universal approach, so if you have application A the tools will work for application B as well. I know Maya Alias Automotive and Rhino. Commands are different named or have different dialogs but essentially do the same.
The area I am particularly interested in is how you can combine polygon and NURBS in one workflow. That is why I mentioned Fusion
as it has an SDS module like Blender but can convert the mesh then into NURBS patches as well. In two month the software will include also 3D sketch curves and then will behave more like Rhino. But I think it will not be free at that point anymore.
I also forgot to mention while it is not 100% the same Blender can simulate the NURBS trim tool with booleans. The only thing you will not have are fillets and blends. The new bridge command can however along even edges generate great flows. And the fill tool has a 4 side edge patch tool option now as well.
The math precision of NURBS is hard to beat and till today I did not see one SDS car that would be as even and correct as done with NURBS. But if this is a hobby for you why not trying to make it all in Blender with the tools it has?
The precisions is more needed to manufacturing anway.