Animation (Animate CC)
CelAction https://www.celaction.com/ - Windows
Pretty much saved the UK animation industry. Serious professional level animation software.
Animation Paper https://animationpaper.com/ Windows, Mac
Development continues on a new modernized version. Excellent frame-by-frame traditional animation software.
interactive 2d Animation (Animate CC)
Godot - https://godotengine.org/ Windows, Linux, Mac
Perhaps a seemingly odd inclusion, but Godot offers arguably better animation and interactive scripting tools than Animate CC. Drawing tools are missing, however.
CanvasXPro https://www.canvasgfx.com/products/canvas-x-pro - Windows
Technical drawing/Technical writer DTP. Aimed at CAD industry
Pagestream https://www.pagestream.org - Windows, AmigaOS, Linux, Windows, Mac
DTP software, from the old Amiga days, but still (slowly) developed.
Microsoft Publisher https://www.microsoft.com/en-us/microsoft-365/publisher Windows
‘Free’ with Office 356.
Ready-Set-Go https://www.diwan.com/index.php/products/desktop-publishing Windows, Mac
Old-fasioned, but still developed?
A German developed free / premium paid features DTP tool exists as well, but I forget its name.
JustInMind Prototyper https://www.justinmind.com/ - Windows/Mac
This is a well-known and widely used prototyping tool. Much more feature-rich compared to XD. More on the level of Axure: these two used to compete before the advent of other popular tools such as Figma and XD.